Medication package insert
IV preparation instructions:
Dilute IV solution using either sterile water for injection or 0.9% sodium chloride solution. Use an equal volume of diluent as the volume of undiluted lorazepam.
The nurse is caring for a client having a tonic-clonic seizure who is prescribed 4 mg lorazepam IV push STAT. What is the total volume of reconstituted lorazepam in milliliters per dose (mL/dose) to be administered? Click the exhibit button for additional information. Record your answer using a whole number.
Correct Answer: 4 mL/dose
Using dimensional analysis, perform the following steps to calculate the total diluted volume in milliliters per dose of lorazepam:
Identify the prescribed, available, and required medication information
Prescribed: 4 mg lorazepam / dose Available: 2 mg lorazepam / mL Required: mL lorazepam / dose
Convert the prescription to the volume of lorazepam in milliliters per dose
Prescription × available medication = mL lorazepam / dose
OR
( mg lorazepam / dose ) ( mL / mg lorazepam ) = mL lorazepam / dose
OR
( 4 mg lorazepam / dose ) ( mL / 2 mg lorazepam ) = 2 mL lorazepam / dose
Add the dilution volume to the medication for total administration volume
Concentration: 1 mL diluent per 1 mL lorazepam
OR
2 mL lorazepam + 2 mL diluent = 4 mL total solution
Educational objective:
To calculate the total administration volume in milliliters of lorazepam, the nurse should first identify the prescribed dose (eg, 4 mg), available medication (eg, 2 mg/mL), and diluent needed (eg, 1 mL diluent per 1 mL lorazepam) and then calculate the total milliliters per dose (eg, 4 mL/dose).
The formula method is an alternate way to calculate medication dosages. However, this method may increase the occurrence of miscalculation and medication errors. If you choose to use this method, do not round any calculations until the final step.
Using the formula method, perform the following steps to calculate the total diluted volume in milliliters per dose of lorazepam:
Convert the prescription to the volume of lorazepam in milliliters per dose
Prescribed dose / required concentration × volume = mL lorazepam / dose
OR
4 mg lorazepam / 2 mg lorazepam x mL = 2 mL lorazepam / dose
Add the dilution volume to the medication
Concentration: 1 mL diluent per 1 mL lorazepam
OR
2 mL lorazepam + 2 mL diluent = 4 mL total solution